The FDA analysis by Dr. Marc Stone, Dr. Thomas Laughren and colleagues involved a review of data from eight drug makers on 372 clinical trials involving nearly 100,000 adults.
Overall, they found the risk of suicide was “strongly age-dependent,” with higher risks in people under 25, no difference among those 25 to 64, and lower risks in people 65 and older.
Because of the FDA’s concerns, drug manufacturers have revised their warning labels to state that young adults — 18-24 years old — may be at an elevated risk of suicidal thought and behavior while using these medications.
Approximately 41 percent of our military forces serving on the front lines in Afghanistan and Iraq are within this same age range. In addition, 40 percent of Army suicide victims in 2006 and 2007 are believed to have taken some type of anti-depressant medication.
Where once drugs were seen as poisons to be used judiciously and with caution, they are now treated as fertilisers whose more or less indiscriminate use can only do good. Where once farmers knew to keep their cattle out of fields growing the serotonin reuptake inhibiting weed, St John’s Wort, as it caused miscarriages, under industry influence women have been herded by doctors in exactly the opposite direction.
GPs are still prescribing an antidepressant known to cause birth defects in unborn children to thousands of women every year, it emerged last night. Pills such as Seroxat may result in babies being born with malformed hearts if taken in the first few weeks of pregnancy – a time when many women are still unaware they may have conceived.
Since the horror of the Thalidomide scandal in the 1960s, pharmaceutical companies and medicines regulators have been acutely aware of the dangers drugs may pose to the unborn child.
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